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br Introduction Noncanonical nucleoside triphosphates NTPs
2020-05-08
Introduction Noncanonical nucleoside triphosphates (NTPs; such as deoxyinosine triphosphate (dITP), deoxyxanthosine triphosphate (dXTP), 8-oxo-deoxyguanosine triphosphate, and 2-oxo-deoxyadenosine triphosphate are produced from oxidation, deamination, or other modifications of canonical nucleotid
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Citrus plants are of great interest
2020-05-08
Citrus plants are of great interest because they contain large amounts of flavonoids, and citrus fruits and their juices are consumed in large quantities around the world [18]. The flavonoid contents and profiles of citrus juices vary greatly with the type of fruit. It has been determined that citru
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chk1 Previous studies reported that NE and
2020-05-08
Previous studies reported that NE and MHPG are deeply involved in depression and that NE reuptake inhibitors are approved for use in patients with depression (for review, see [2]). We found increased hippocampal content of NE and MHPG in the CORT-treated CRTH2−/− mice (Fig. 3). In the hippocampus, a
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br Material and methods br Results
2020-05-08
Material and methods Results Discussion Conclusions To conclude, although CPT2 and CPT1 must have co-evolved to establish the carnitine shuttling, these enzymes are the most distantly related carnitine transferases, split early in evolution, during which a switch occurred in their locati
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Chk is dramatically induce by the IL family
2020-05-08
Chk is dramatically induce by the IL-4 family of cytokines and equally dramatically inhibited by IFN-γ, a regulation that appears to be specific for human monocytes. In primary human T cells, Chk is not normally present, but it can be induced by potent activators of T HOSu such as PHA or IL-2 ((McV
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Currently phosphodiesterase type PDE inhibitors
2020-05-08
Currently, phosphodiesterase type 5 (PDE-5) inhibitors are used widely as the first- line oral treatment for erectile dysfunction of varying causes. Radical prostatectomy for the treatment of prostate cancer is frequently associated with erectile dysfunction, and this type of erectile dysfunction is
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In conclusion the results obtained in this study and those
2020-05-08
In conclusion, the results obtained in this study and those recently reported by our group (Abdel-Samad et al., 2012) clearly indicate that a dialogue indeed exists between the systems of NPY and ET-1 at the level of human endocardial endothelial cells, since these cells, whether isolated from the r
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br Introduction The cervix is
2020-05-08
Introduction The Fmoc-Tyr(tBu)-OH mg is a poorly studied component of the mare’s reproductive tract. It has anatomical and biological defense mechanisms involved in the delicate balance between immunological tolerance, sperm transport and biological defense. Anatomically, the cervix is composed
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Identification of the drug to be used as first
2020-05-08
Identification of the drug to be used as first-step antihypertensive treatment has always been, and remains, a matter of debate. The decision wihich drug (or drug combination) to choose as first-line therapy depend on many variables such as coexisting metabolic disorders, obesity, presence of subcli
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First of all two assumptions
2020-05-08
First of all, two assumptions just as in Ref. [30] are need to simplify the penetration process: (1) The crater phases is short and the Cy3 NHS ester (non-sulfonated) australia of EFP is consumed little; thus, the influence of crater on penetration can be ignored; (2) the initial stagnation radial
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Pefloxacin I bungarotoxin competes with ACh an endogenous ac
2020-05-08
[125I] α-bungarotoxin competes with ACh, an endogenous activator of α7-nACh receptors by binding to the ACh binding site on the receptor (Albuquerque et al., 2009). For this reason, the effect of curcumin was investigated on the specific binding of [125I] α-bungarotoxin. Saturation curves for the bi
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CRF and urocortin I are not only
2020-05-07
CRF and urocortin I are not only readily found throughout the spinal cord (Korosi et al., 2007), CRF analogs are clearly able to alter nociceptive signals (Imbe et al., 2010; Lariviere and Melzack, 2000). However, it was unclear whether they are released endogenously and involved in the spinal modul
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5 alpha reductase inhibitor br Material and Methods br Resul
2020-05-06
Material and Methods Results and Discussion Conclusions Two chemical coupling agents, BTDE and CDI, were used to activate the free hydroxyl groups of plant cellulose powder and OPH from Flavobacterium ATCC 27551 immobilized on modified carriers by covalent linkages. The highest immobilizati
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For this study we have used the intermediate
2020-05-06
For this study we have used the intermediate affinity mutant antigen HEL2× for immunization. However, we have observed a similar defect in the plasmablast differentiation of EBI2-deficient SWHEL Biotin-16-dCTP over a 10,000-fold affinity range by using WT HEL or the low-affinity mutant HEL3× (data n
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br Results and Discussion br Experimental Procedures br
2020-05-06
Results and Discussion Experimental Procedures Acknowledgments The ubiquitin–proteasome system (UPS) is important for biological processes such as protein degradation and protein function regulation. In general, poly-ubiquitinated proteins are degraded by proteasomes, and some proteins ac
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