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Pharmacokinetics analysis of AT on
2019-06-17
Pharmacokinetics analysis of AT-406 on SCID mice bearing MDA-MB-231 tumors has shown that AT-406 achieves a maximum concentration in plasma between 1.5μM and 9.9μM, and a maximum concentration in tumor tissue between 0.5μM and 18.2μM, depending on the dose and administration route (intravenous versu
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RQ-00203078 In the current era nearly all cases of hormone
2019-06-17
In the current era, nearly all cases of hormone-receptor positive breast cancer are treated with adjuvant endocrine therapy irrespective of staging, with preference for aromatase inhibitors over tamoxifen because of side effect profile, survival outcome and tumor recurrence rates [4,11]. In our stud
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br Materials and methods br Results CRT
2019-06-15
Materials and methods Results CRT devices were successfully implanted in 27 patients (70.7±10.1 years), and the LV leads were placed in the lateral branch or posterolateral branch. Baseline characteristics of all patients are listed in Table 1. Eighteen of 27 patients received a CRT defibrilla
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The principal difference between BrS
2019-06-15
The principal difference between BrS and ERS is related to the region of the ventricle most affected. Epicardial mapping studies in BrS patients report accentuated J waves and fragmented and/or late potentials in the epicardial region of the RVOT [129–131], whereas in ERS only accentuated J waves, p
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br Results As shown in Table the
2019-06-15
Results As shown in Table 1, the amplitude, and the onset or the end of LA potentials were successfully determined via visual inspection. Among 19 patients with AP, LA potentials were detected in 7 (37%), all in an LA → CSM activation sequence (Fig. 2). In contrast, among 21 patients with CCW AFL
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Celecoxib cost Performance based financing often highlighted
2019-06-15
Performance-based financing, often highlighted in Rwanda\'s story, has had mixed results when applied elsewhere, partly because of breakdowns in execution. For example, the failure of the performance-based financing initiative in neighbouring Uganda was caused by challenges in setting targets, deliv
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We also demonstrated by ELISA ELISPOT and CTL assays the
2019-06-14
We also demonstrated by ELISA, ELISPOT and CTL assays the capacity of alum to induce a Th1 immune response. The evaluation of the secreted frizzled related protein response against LALF32-51 peptide, E7 protein and LALF32-51-E7 fusion protein in immunized mice suggest that the antibodies response ge
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Our research in this area has been focused on
2019-06-14
Our research in this area has been focused on understanding the highly vascular nature of RCC, which has been largely attributed to loss of function of the von Hippel-Lindau (VHL) gene and resultant vascular endothelial growth factor (VEGF) over-expression, as it is an early event during tumorgenesi
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Brugada syndrome BS is a hereditary arrhythmogenic disease
2019-06-14
Brugada syndrome (BS) is a hereditary arrhythmogenic disease characterized by a coved- or saddleback-type ST elevation in the right precordial lead on a 12-lead electrocardiogram (ECG) and ventricular fibrillation (VF) occurring mainly at night. During the past 2 decades, since Brugada and Brugada
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Introduction Paraneoplastic immune mediated encephalopathy i
2019-06-14
Introduction Paraneoplastic immune-mediated encephalopathy is a newly described disease. In 2005, Vitaliani et al first reported that four young women with ovarian teratoma (OT) had developed acute psychiatric and neurologic symptoms, e.g., seizures, memory deficits, decreased level of consciousnes
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br Postoperative rehabilitation Although surgery is the
2019-06-14
Postoperative rehabilitation Although surgery is the main curative therapy for lung cancer, the procedure can directly cause a reduction in pulmonary functional reserve and exercise capacity proportional to the extent of resection. The problems might be more severe in those undergoing multimodali
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order d-amphetamine However despite the strength of the rese
2019-06-14
However, despite the strength of the research by Shawar and colleagues, any given process tracing case study can always be improved. In relation to this Article, the empirical tracing of causal processes could be strengthened further in future research, in particular by telling us more explicitly wh
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Cabe mencionar que en despu s
2019-06-14
Cabe mencionar que, en 2005, después de diez años de trabajar en la Universidad de Pittsburgh, espacio de gran relevancia para la gestación de las antologías analizadas, Moraña se trasladó herpes simplex virus infection la Universidad de Washington en St. Louis, donde, hasta la fecha, pasó a fungir
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Cambiemos de hemisferio y procedamos a
2019-06-13
Cambiemos de hemisferio y procedamos Bleomycin Sulfate viajar al Cusco del siglo xvi. La doctrina o parroquia que es de interés aquí –San Cristóbal Qolqanpata– parece haber sido administrada inicialmente por unos intermediarios apostólicos que poco o nada tuvieron que ver con la orden de San Francis
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Previous studies have demonstrated localization of miR stain
2019-06-13
Previous studies have demonstrated localization of miR-21 staining in stromal synthesi of OSCC associated with the tongue and mouth floor—this might be a useful prognostic predictor. We also observed miR-21 staining in the stromal cells of tumors. However, since multiple lines of evidence indicate t
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