• Patients with endophytic tumors had

  2019-05-07

  

  Patients with endophytic tumors had a 2.6-fold higher rate of local recurrence than those with exophytic tumors. The 5-year local control rates were 64% and 95% in those with endophytic and exophytic lesions, respectively. The correlation of tumor morphology with local recurrence in patients with ea

• br Conclusion and future directions br Conflict of interest

  2019-05-07

  

  Conclusion and future directions Conflict of interest Acknowledgments Introduction Epithelial-mesenchymal transition (EMT) is a process by which epithelial MLN 9708 lose their polarity and are converted to a mesenchymal phenotype; recently, this has been regarded as the critical event t

• This patient had sick sinus syndrome and also

  2019-05-07

  

  This patient had sick-sinus syndrome and also took sotalol for the prevention of VT related to ARVC. Therefore, constant atrial pacing was indispensable for maintaining a physiological atrial rhythm. Frequent right ventricular pacing is known to cause left ventricular dysfunction, myocardial perfusi

• Depending on the target gene

  2019-05-06

  

  Depending on the target gene, KLF4 may function as both a repressor and activator of transcription [31,32]. Previous studies demonstrated Bax could be a tumor-suppressor target of KLF4 functioning as an anti-oncogene [33,34]. When transfected with anti-miR-367, MG-63 and U2OS things showed enhanced

• Funding secured by Not applicable Data collection Sheldon M

  2019-05-06

  

  Funding secured by: Not applicable. Data collection: Sheldon M. Singh, MD, Ramanan Kumareswaran, MD. Conflict of interest Acknowledgments Introduction Early repolarization pattern (ERP) is characterized by an elevation greater than 0.1mV of the junction between the end of the QRS complex

• A preserva o da ideia de fam lia

  2019-05-06

  

  A preservação da ideia de família tradicional tornou-se uma das principais demandas desses representantes. Neste sentido, o Projeto de Lei n° 6583 de 2011, conhecido como Estatuto da Família, almeja o reconhecimento (pelo Estado) da família como uma entidade formada apenas por um homem, uma mulher e

• br Conclusion br Authors contribution br

  2019-05-06

  

  Conclusion Authors’ contribution Competing interests Acknowledgments Case report Imatinib has radically changed prognosis in chronic-phase Chronic Myeloid Leukemia (CML), with 90% overall survival rate at 8yrs, and 40–70% of patients achieving a stable MMR [1]. Even better results hav

• Interpretation Stakeholders from sectors not historically en

  2019-05-06

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North

• Our research in this area has been

  2019-05-06

  

  Our research in this area has been focused on understanding the highly vascular nature of RCC, which has been largely attributed to loss of function of the von Hippel-Lindau (VHL) gene and resultant vascular endothelial growth factor (VEGF) over-expression, as it is an early event during tumorgenesi

• br Methods br Results br

  2019-05-05

  

  Methods Results Discussion A. baumannii remains one of the most common nosocomial pathogens and frequent causes of outbreaks in burn wound infections. Unfortunately, most of the isolates are resistant to antimicrobial agents. β-Lactamases are microbial enzymes that hydrolytically inactivate

• Amongst other anti arrhythmic medications disopyramide class

  2019-05-05

  

  Amongst other anti-arrhythmic medications, disopyramide (class 1A AAM) has anticholinergic side effects such as dry mouth, urinary hesitancy, constipation and exacerbation of conditions like glaucoma and myasthenia gravis. Disopyramide acts by targeting the fast sodium erk pathway in the cardiac ti

• order OG-L002 En ese encuentro de intereses entre los distin

  2019-05-05

  

  En ese encuentro de intereses entre los distintos grupos, bien sea por dominar el territorio, o por imponer la fuerza, o bien por controlar el negocio del narcotráfico, la población queda expuesta y vulnerable. Los ataques entre unos y otros tienen serias repercusiones sobre los poblados “las accion

• br Results br Discussion Atrial fibrillation is widely recog

  2019-05-04

  

  Results Discussion Atrial fibrillation is widely recognized as the most common sustained arrhythmia. The risk of AF development may be determined by evaluating the patients’ age, sex, underlying Axitinib disease, other medical illnesses, and echocardiographic findings. However, better predicto

• br Discussion The present meta analysis of randomized trials

  2019-05-04

  

  Discussion The present meta-analysis of randomized trials demonstrated that treatment with AAMs is associated with an increase in non-cardiac and all-cause mortality as compared to non-arrhythmic therapy or control group. There was no significant reduction in cardiac or arrhythmic mortality betwe

• br Genetic basis for atrial standstill br Genetic

  2019-05-04

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

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