• It is also possible that primary therapies directed

  2019-04-29

  

  It is also possible that primary therapies directed at the tumour might have had an effect on the time trend results. While the primary therapy practice has not changed; the proportion of patients receiving it wst-1 has. For example, since the introduction of docetaxel in prostate cancer, across th

• To date two trials have

  2019-04-29

  

  To date, two trials have been presented assessing reduced frequencies of administration of these agents in metastatic breast cancer patients [12,13] and others are still on going [17]. Despite this, the results of the published trials would suggest that there is still a need for larger definitive st

• Introduction Cardiac resynchronization therapy CRT reduces

  2019-04-29

  

  Introduction Cardiac resynchronization therapy (CRT) reduces mortality and morbidity in selected heart failure patients with impaired left ventricular (LV) function and cardiac dyssynchrony [1]. Most patients receive CRT with a defibrillator (CRT-D) because the indications for an implantable cardio

• br Update on the diagnosis of

  2019-04-29

  

  Update on the diagnosis of ERS ERS is generally diagnosed in patients who display ER in the inferior and/or lateral leads presenting with aborted cardiac arrest, documented VF, or polymorphic VT. Consistent with the recent consensus report on ERP [24], ER is recognized if (1) there is an end QRS

• De esta manera tenemos una novela nacional en la

  2019-04-29

  

  De esta manera, tenemos una novela nacional en la que parecería que no se manifiesta de manera patente la promesa de la consolidación de la nación. La crítica ha propuesto la explicación del final trágico como una lección moralizante y/o una crítica de mujeres caprichosas… ¿pero acaso el final de ,

• The risk of exacerbation can be assessed in

  2019-04-29

  

  The risk of exacerbation can be assessed in several ways: symptoms, use of medication, and admission to hospital. However, several questions remain to be answered in Chinese clinical practice. For example, the time of an acute exacerbation is often inaccurate because many patients have a poor unders

• Obeticholic Acid br Chronic obstructive pulmonary disease CO

  2019-04-29

  

  Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. It is one of the most common non-communicable diseases, affecting 329 million people, and this number is likely to be an underestimate. The global economic cost of COPD is US$2·1 trillion. Yet it remains al

• Si bien en Argentina la democracia

  2019-04-29

  

  Si bien en Argentina la democracia se alcanzó por el colapso de la dictadura, la guerra de Malvinas, la misma estaba planifi en las “Bases para la Intervención de las Fuerzas Armadas en el Proceso Nacional”. En este documento se indicaba que el proceso se desarrollaría mediante la ejecución de tres

• OTX-015 br Worldwide it has been recognised that violence ag

  2019-04-29

  

  Worldwide, it has been recognised that violence against women and violence against children are significant human rights and public health issues, with WHO describing violence against women as a “global health problem of epidemic proportions”. Globally, a third of women have been the victims of ge

• br Introduction Homocysteine Hcy is a

  2019-04-29

  

  Introduction Homocysteine (Hcy) is a sulfur-containing amino order Sulfo-NHS-LC-Biotin that has a key role in methionine metabolism. Disturbance of this metabolic pathway may result in the accumulation of Hcy and related abnormal outcomes such as cognitive disorders, cancer, and birth defects. In

• De esta manera la ideolog a

  2019-04-28

  

  De esta manera la ideología pos-Stonewall alentó el rechazo de previas y abyectas formas de gaycidad. El Journal of Homosexuality de San Francisco publicó, desde 1976 y hasta comienzos de los años ochenta, varios artículos en los cuales se sostenía que, contrariamente beta 3 agonist todos los viejo

• Definida pelo Estado como crit rio inicial

  2019-04-28

  

  Definida pelo Estado como critério inicial para o andamento das reivindicações quilombolas por reconhecimento e consequentemente RO5185426 políticas públicas e representatividade política, a autoatribuição pode soar simplista se preestabelecermos que os agrupamentos negros só reafirmam uma identidad

• Since I created the Doughnut at Oxfam

  2019-04-28

  

  Since I created the Doughnut at Oxfam in 2012, it has been widely applied within academia, policymaking, progressive business, urban planning, and civil society as a tool for reconceptualising sustainable development. Here I present a renewed and strengthened framework, based on recent advances in b

• The study by Marshall Burke and colleagues evaluated geospat

  2019-04-28

  

  The study by Marshall Burke and colleagues evaluated geospatial trends in under-5 mortality from 82 Demographic and Health Surveys in 28 countries in sub-Saharan Africa. The investigators used a 10 km × 10 km matrix to map under-5 mortality and assessed the association between changes in mortality a

• MIP binds to three different receptors CCR CCR and

  2019-04-28

  

  MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM melatonin receptor agonist and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues dem

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