• Since I created the Doughnut at Oxfam

  2019-04-28

  

  Since I created the Doughnut at Oxfam in 2012, it has been widely applied within academia, policymaking, progressive business, urban planning, and civil society as a tool for reconceptualising sustainable development. Here I present a renewed and strengthened framework, based on recent advances in b

• The study by Marshall Burke and colleagues evaluated geospat

  2019-04-28

  

  The study by Marshall Burke and colleagues evaluated geospatial trends in under-5 mortality from 82 Demographic and Health Surveys in 28 countries in sub-Saharan Africa. The investigators used a 10 km × 10 km matrix to map under-5 mortality and assessed the association between changes in mortality a

• MIP binds to three different receptors CCR CCR and

  2019-04-28

  

  MIP-1α binds to three different receptors: CCR1, CCR5 and CCR9. CCR1 and CCR5 are expressed on MM melatonin receptor agonist and stromal cells. Inhibitors to CCR1 and CCR5 have been used to delineate the roles of each receptor in the myeloma bone marrow microenvironment[69]. Menu and colleagues dem

• br Discussion Compared to the right ventricular outflow trac

  2019-04-28

  

  Discussion Compared to the right ventricular outflow tract, the LVOT has a more complicated anatomic structure, comprising the mitral annulus, aortic cusps, and LV basal myocardium. The AMC bridges the aortic and mitral valves with fibrous tissue, called the left fibrous trigone [3], and the exte

• br Conflict of interest br Introduction Catheter ablation

  2019-04-28

  

  Conflict of interest Introduction Catheter ablation is an effective approach for the management of patients with atrial fibrillation (AF) [1–7]. Pulmonary vein isolation (PVI) is one of the most common strategies of AF ablation, but the outcome of PVI alone for patients with persistent AF is p

• The region is also suffering from

  2019-04-28

  

  The region is also suffering from administrative negligence, extreme poverty, lack of basic health facilities, and weak infrastructure, which have increased its vulnerability to the climatic misery. Travel time to the nearest health facility is 2–4 h, at a cost of PKR 1000–4000 (US$10–40) in a regio

• El resultado de esta reuni n

  2019-04-28

  

  El resultado de esta reunión se plasmó en una serie de resoluciones que transcribe Elena Aub en su libro sobre el me/59. En resumen, se acordaba un programa de máximos para España en el que se señalaba el restablecimiento de todas las libertades políticas, el derecho de autodeterminación de Cataluña

• Although the NCCN IPI is a promising simple scale based

  2019-04-28

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• Findings Three factors were significant predictors of treatm

  2019-04-28

  

  Findings Three factors were significant predictors of treatment failure: the presence of at least 1 month of fair or poor adherence (OR 15·7, 95% CI 1·8–136·7; p=0·01); previous treatment at another clinic before the WWO/AHF Family Health Clinic (1·4, 1·2–13·7; p=0·02); and tuberculosis symptoms at

• In another study Lopez and associates found that patients wi

  2019-04-26

  

  In another study Lopez and associates found that patients with chronic heart failure receiving torsemide, a loop diuretic that inhibits the enzyme involved in the myocardial extracellular generation of collagen type I molecules (i.e., procollagen type I carboxy-terminal proteinase or PCP), had reduc

• Any abnormality causing a loss

  2019-04-26

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• angiotensin receptor blockers En definitiva se trataba de bu

  2019-04-26

  

  En definitiva, se trataba de buscar un “origen” de la literatura y cultura latinoamericana, no afincado en las textualidades del siglo xix o en un momento tar-docolonial, sino en aquellos textos “fundantes” en los que todo parecía posible: las crónicas de conquistadores y soldados, los conmovedores

• Although second malignancies are increasingly observed after

  2019-04-26

  

  Although second malignancies are increasingly observed after NHL, the incidence of CLL and RCC in the same patient is exceptional [4,5]. Nishikubo et al. [4] reported a case series of 8 patients with lymphoid malignancies and RCC. In 2 of 8 patients, CLL and T-cell CLL were diagnosed 1 year and 8 mo

• Introduction Atrial fibrillation AF is the most

  2019-04-26

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• br Conclusions br Conflict of

  2019-04-25

  

  Conclusions Conflict of interest Introduction Case report A 26-year-old woman in the 19th week of her first pregnancy presented with a chief complaint of palpitations. Electrocardiogram (ECG) showed sustained AT with heart rate (HR) of 180bpm. The P wave morphology was positive in the in

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