• br Conflict of interest br Acknowledgements This work

  2018-11-05

  

  Conflict of interest Acknowledgements This work was funded by King Abdulaziz University, under Grant no. (D-004/431). The authors, therefore, acknowledge technical and financial support of KAU, Saudi Arabia. Introduction Inverse problems is a branch of research whose scope can be broadly d

• The paper is organized as follows the materials and methods

  2018-11-05

  

  The paper is organized as follows, the materials and methods are discussed in Section 2, the results and discussion are presented in Section 3, and the conclusion is summarized in Section 4. Materials and methods Results and discussion The detector system was fabricated in a 0.18μm standard C

• Tumor relapse after radiotherapy is a significant challenge

  2018-11-03

  

  Tumor relapse after radiotherapy is a significant challenge to oncologists. Tumor recurrence was generally due to radiation resistance, which was determined by both the intrinsic characteristics and the extrinsic microenvironment of cancer Torin1 (Frank et al., 2010). The unique stem cell properties

• The vaccine development approach pursued by the GSK

  2018-11-03

  

  The vaccine development approach pursued by the GSK Vaccines Institute for Global Health (GVGH) is based on Generalized Modules for Membrane Antigens (GMMA). GMMA are approximately 50nm outer membrane blebs derived from bacteria genetically modified to enhance shedding and to reduce reactogenicity o

• Here we report that the Tim galectin autocrine

  2018-11-03

  

  Here we report that the Tim-3-galectin-9 autocrine loop is activated in AML Volasertib through protein kinase C (PKC)/mTOR pathways. These pathways trigger translation of both Tim-3 and galectin-9 and induce high levels of galectin-9 secretion as well as the release of soluble Tim-3. Importantly, t

• For the calculation of the bulk value of

  2018-11-03

  

  For the calculation of the bulk value of the Young׳s modulus the simplest choice is a 2-atom tetragonal unit cell with cell vectors along [], [110], and [001]:This cell, however, does not allow to introduce twin boundaries. Therefore, the calculation of was repeated for a second, 6-atom orthorhombic

• br Acknowledgments The authors wish

  2018-11-03

  

  Acknowledgments The authors wish to acknowledge co-funding of this work by Spain׳s Ministry of Economy and Competitiveness (MINECO-INIA-CCAA) and the European Fund of Regional Development (FEDER, Grant RTA2011-00020-C02-02). The staff at the Central Service for Research Support (SCAI) of the Univ

• metabotropic glutamate receptor br Experimental design mater

  2018-11-03

  

  Experimental design, materials and methods Acknowledgements This work was supported by the Ministry of Health and Welfare of Korea. (Grant no. HI12C1154). Data We compared the ELISA with Western blot data from C2C12 myotubes and male wild-type C57BL/6 mouse metabotropic glutamate receptor

• A large number of neuroimaging studies in adults and

  2018-11-03

  

  A large number of neuroimaging studies in adults and school-aged children show that reading involves a left lateralised neural network, with a dorsal interaction between left frontal (in and around Broca) and temporoparietal regions to sustain phonological processing and grapheme-phoneme decoding (S

• A benefit of two photon imaging techniques over

  2018-11-03

  

  A benefit of two-photon imaging techniques over traditional postmortem histology is that we are able to follow the stability of individual synaptic structures over multiple days. Analysis revealed that the stability of previously established structures was typically age-dependent while stabilization

• dhpg A growing body of literature

  2018-11-03

  

  A growing body of literature suggests that Major Depressive Disorder (MDD) is associated with impaired cognitive control processes necessary for effective emotion regulation (Diener et al., 2012). These impairments are often coupled with ineffective or maladaptive regulation strategies that may exac

• br Results Fig a shows the general cognitive

  2018-11-03

  

  Results Fig. 1a shows the general cognitive ability heritability estimates for children, adolescents, and adults, re-plotted from Brant et al. (2013). Given the reported high heritability of cognitive ability, we focused on the simulated population where heritability was highest, that is, the pop

• If toddlers distinguish between grammatical

  2018-11-03

  

  If toddlers distinguish between grammatical and ungrammatical sentences on the basis of the relative frequency of word strings (pairs, triplets, or more generally n-grams), this would imply that they rely on memorized chunks of sentences and may not be able of a more abstract processing based on syn

• Structural brain imaging studies have been less

  2018-11-03

  

  Structural cyclosporin imaging studies have been less informative. Only two studies have investigated the neuroanatomical correlates of guilt; one found a significant negative association between trait guilt and insula cortex volume (Belden et al., 2015), while a second study found a positive assoc

• br Conflict of interest br Acknowledgments This study

  2018-11-03

  

  Conflict of interest Acknowledgments This study was funded by the UK Medical Research Council (MRC) (G0802226) and the Behavioural and Clinical Neuroscience Institute (BCNI) at the University of Cambridge (jointly funded by the MRC and Wellcome Trust). Additional support was given by the Natio

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